Team Powerpuff head to Hills Village Middle School, where they meet a student named Rafe Khatchadorian who's into drawing things. Unfortunately, the middle school is ruled by Principal Dwight, whose strict rules are enforced in the entire school. The gang makes it their goal to break every single rule in the Code of Conduct and get their freedom.
The Powerpuff Girls: Blossom, Bubbles & Buttercup
The Chipmunks: Alvin, Simon & Theodore
Garfield & Odie
the Teenage Mutant Ninja Turtles: Leonardo, Donatello, Raphael & Michelangelo
Yoshino Fujieda & Lalamon